If this sounds like you, Re2O
When you want to rebuild the foundation of the skin that topical care cannot fill.
- Those with enlarged pores and rough texture that makes makeup flake
- Those starting to notice reduced firmness and fine lines or neck wrinkles
- Those with hollow, thinning under-eyes that look shadowed and lined
- Those who want fundamental regeneration that fills in from within rather than a temporary fill
Beyond filling - rebuilding
The world's first ECM solution
Not simply hydration or nutrition, but a new kind of skin booster that fills the skin's structure itself.
Re2O directly replenishes ECM (extracellular matrix), the framework of the skin, based on human acellular dermal matrix (hADM). It is an ECM skin booster that helps a weakened skin environment recover, building a foundation where cells work again and collagen can fill in.
Human-derived dermis, its structure just as it is
added to the skin
hADM · human Acellular Dermal Matrix
Re2O is a human tissue allograft made by micronizing ECM obtained from strictly processed human acellular dermal matrix (hADM). Because it replenishes ECM with the same structure as the dermis of our own skin, it helps restore the skin's natural regenerative environment without a sense of foreignness.
* Re2O is a human tissue allograft lawfully and safely processed under the Act on Safety and Management of Human Tissue and Good Tissue Practice (GTP).
The foundation that supports the skin, the ECM Scaffold
ECM is the home where cells settle and work, and the framework that supports the skin's structure.
Scaffold Extracellular matrix
Structural support
It forms the firm framework that supports the skin's structure.
Moisture retention
It holds moisture from within, keeping a hydrated environment.
Cell adhesion & migration
It becomes the scaffold on which cells settle and move.
Elasticity
It builds a collagen and elastin environment, creating a base for firmness.
Wound healing & regeneration
It creates a regenerative environment in which damaged tissue recovers.
Beyond inducing collagen production
It induces remodeling of the dermal structure
After injection, it directly provides an ECM scaffold where cells can work.
Even distribution
Micro particles settle evenly in the skin without damaging the dermal structure.
New collagen formation
Interaction with cells promotes new collagen formation (neocollagenesis).
Angiogenesis & regeneration
It increases growth factors such as VEGF, FGF and PDGF, creating angiogenesis and an environment for regeneration.
Alive within the micro particles
The skin's own components
Even after micronization, the fibrous structure of collagen (D-band) is preserved as it is.
Four technologies behind Re2O
Precise processing that preserves the material's structure and raises safety
Micronized ADM
A micronized powder-type material, making it easy to adjust dose and concentration by treatment area and purpose.
TRI-CORE™ Technology
Refined micronization preserves the three-dimensional structure of collagen and ECM components as they are, optimizing the regenerative environment.
SFDcell™ Technology
A special decellularization process without surfactants reduces residual cells and chemicals, lowering the likelihood of an immune response.
Global standard quality certification
Tissue banks approved by the Korean MFDS and the AATB observe strict standards for raw material, processing, quality and distribution.
Re2O in video
See Re2O in video.
Video coming soon
One injection, the change at 4 weeks
Efficacy assessment results at week 4 after a single Re2O injection.
Re2O Full face · neck
Re2O Fine Under-eye · neck
* Based on the manufacturer's (Humedix) clinical evaluation data (Int J Mol Sci. 2026;27(5):2193), measured at week 4 after a single injection. Results may vary with individual skin condition.
Two types of Re2O, designed for each area
From broad-area regeneration to the delicate eye area, particle size and dose are adjusted to fit.
Re2O
A standard line that broadly fills texture, firmness and pores across the whole face.
- Volume150 mg
- Average particle size75 µm
- Treatment areaFull face · neck
Re2O Fine
A finer-particle delicate line for the thin, sensitive under-eye area.
- Volume50 mg
- Average particle size50 µm
- Treatment areaUnder-eye · neck
Because it is human tissue, safety comes first
From an internationally certified tissue bank to the treatment itself, the entire process is tracked.
Allograft use across a range of clinical fields*
The L&C BIO tissue bank follows strict processes from donor screening through processing, quality and distribution, in line with the human tissue guidelines of the AATB and the Korean MFDS.
Donor eligibility screening
Thorough eligibility screening - donor medical history and cause of death, infectious disease and blood and virus testing - raises the level of safety.
Tissue processing & sterilization
Immune response factors are removed and viral inactivation is carried out, followed by a sterilization process to lower potential infection risk.
Distribution & traceability
A unique identification number on the final product allows the entire cycle from distribution to graft to be tracked.
* Cumulative use of L&C BIO allograft material, 2016.01~2026.01.
What it means to add skin to skin
Not beauty layered on top, but beauty rebuilt.
ECM replenishment
New collagen
Rising regenerative power
1:1 tailored design
